In Asian medicine, celery seed is used to treat headaches and as a diuretic, digestive aid, and emmenagogue. Heck AM, DeWitt BA, Lukes AL. Int Arch Allergy Immunol 2005;136(3):230-238. The effect of celery and parsley juices on pharmacodynamic activity of drugs involving cytochrome P450 in their metabolism. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. A Root Vegetable With Surprising Benefits, 10 Delicious Herbs and Spices With Powerful Health Benefits, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, Parmesan Cheese: Nutrition, Benefits, and Uses. Ko FN, Huang TF, Teng CM. Celery is known to be dangerous for allergic individuals. A study in Preventive Medicine and Food Science, published in June 2018, investigated the effect of celery and its hydroalcoholic extracts on the treatment of gout. View abstract. Celery Seed Extract: Benefits, Side Effects & Dosage, celery seed extract for high blood pressure, Ectopic Pregnancy: Characteristics, Causes & Treatment , Cayenne Pepper: Benefits, Side Effects & Dosage. Celery seeds contain many of these important nutrients. Moneret-Vautrin, D. A. and Kanny, G. [Food-induced anaphylaxis. DOI: Vieira AT, et al. Celery root extract might decrease how quickly the body breaks down venlafaxine. Celery seed has been used as medicine for thousands of years in the Eastern world. This could make the effects of blood thinners stronger and raise the risk of bleeding. Raised liver enzymes have been noted with higher doses of dl-3-n-butylphthalide, a synthesized version of an extract from seeds of A. graveolens (l-3-n-butylphthalide). Celery soup causing severe phototoxicity during PUVA therapy [letter]. However, celery was just one part of their diet. Other constituent compounds have been identified. Combined with anise and saffron, celery seed extract is used to treat menstrual discomfort and reduce fluid retention(x). These benefits might reduce the frequency and severity of painful gout attacks. This compound is thought to relax artery wall tissues to promote healthy blood flow. 3-31-1984;13(14):871-874. Presse Med. Xanthine oxidase is an enzyme in the purine pathway, which produces the by-product of uric acid. More importantly, celery seeds may be useful in the treatment of hypertension help normalize blood pressure.(x). This information is not specific medical advice and does not replace information you receive from your health care provider. In an Australian study, mice suffering from arthritis and gout took a combination of Indian celery seed extract and New Zealand green-lipped mussels. Iron deficiency is the most common micronutrient deficiency worldwide, but eating more iron-rich foods has been shown to lower your risk of deficiency and subsequent anemia (16, 17). Potential interactions between alternative therapies and warfarin. The Department of Pharmacology at the University of Singapore put mice on a high-fat diet for eight weeks. View abstract. Moreover, these compounds fight against certain cancers including intestinal cancer, breast cancer and leukemia by preventing mutated malignant cells from multiplying (x). Infrared spectography has detected another compound with a furocoumarin glucoside, isoquercitrin. Sarshar S, Sendker J, Qin X, et al. But if youre experiencing painful symptoms of gout and are interested in exploring alternative treatment options, speak with your doctor for more information. IgE cross-reactivity between birch pollen, mugwort pollen, and celery is due to three distinct cross-reacting allergens: immunoblot investigation of the birch-mugwort-celery syndrome. Almost 70% of older adults use them. If you have gout, try turmeric as a home remedy. Am J Health Syst Pharm 2000;57:1221-7. Consider therapy modification.Mousa 2010, Spolarilch 2007, Stanger 2012, Ulbricht 2008, Allergy, including dermatitis and anaphylaxis (rare), and phototoxicity to celery and its falcarinol content have been described.Christensen 2006, Duke 2002, Khan 2009, Pauli 1985, Raised liver enzymes have been noted in phase 3 trials of dl-3-n-butylphthalide 800 mg/day.Cui 2013, Celery seed has GRAS status when used as a food.Khan 2009 Neurotoxicity in rats due to the seed's chemical constituent falcarinol has been demonstrated.Christensen 2006 While celery root contains furocoumarins (particularly psoralens), the concentration in normal dietary intake is at least 1,000-fold lower than the no observed effect level for developing liver or cancer in rats.Dolan 2010 Limited toxicological studies suggest celery seed extract lacks toxicity at normal dosages.Powanda 2015. WebOne can use the recommended Oriental dosages to lower mild cases of high blood pressure by eating about four ounces of celery per day. Blood-thinning medications (anticoagulants and antiplatelets): Celery seed contains chemicals that may thin the blood. Celery seeds contain several substances, including: Scientists have not studied celery seeds in children, so it is not recommended for use in children under 18. Celery seed extract. In one in vitro study, it was revealed that luteolin is one of the flavonoids that can inhibit xanthine oxidase. Bonnin, J. P., Grezard, P., Colin, L., and Perrot, H. [A very significant case of allergy to celery cross-reacting with ragweed]. Food Chem.Toxicol. and tightening of the airways, Shock, along with a severe drop WebOral administration of celery seed extract (300 mg/kg) for six weeks prevented an increase in oxidative stress and hepatic enzyme and bilirubin levels. To establish that the product manufacturers addressed safety and efficacy standards, we: We do the research so you can find trusted products for your health and wellness. (2014). Healthline only shows you brands and products that we stand behind. Data sources include IBM Watson Micromedex (updated 1 May 2023), Cerner Multum (updated 17 Apr 2023), ASHP (updated 10 Apr 2023) and others. Consider therapy modification.Mousa 2010, Spolarilch 2007, Stanger 2012, Ulbricht 2008, Thrombolytic agents: Herbs (anticoagulant/antiplatelet properties) may enhance the adverse/toxic effect of thrombolytic agents. But only about 25% of people who take herbal supplements tell their health care providers. Celery seeds consist of the oil (petroselinic, linoleic, palmitic, and oleic fatty acids) and volatile compounds, mostly monoterpene hydrocarbons.Kooti 2017 The major constituents of celery seed oil are d-limonene (60%), selinene (10%), and related phthalides (3%) (eg, 3-n-butylphthalide, sedanenolide, sedanonic anhydride). However, people who take the following medicines should ask their doctors before taking celery seed. Here are 6 surprising benefits of celery seeds. 2010;65(6):792-3. Herbal infusions used for induced abortion. Celery has also been prescribed as an antiflatulent, antilactogen, and aphrodisiac.Al-Asmari 2017, Bisset 1994, Garfield 1985, The celery leafstalk is high in minerals, including sodium, potassium, calcium, magnesium, and iron and nitrates; however, it is a relatively poor source of vitamins except for vitamin C.Afourtit 2015, Meng-Yao 2018. Celery seeds consist of the oil (petroselinic, linoleic, palmitic, and oleic fatty acids) and volatile compounds, mostly monoterpene hydrocarbons.Kooti 2017 The major J Toxicol.Clin Toxicol. J Pharm Pharmacol. Peterson, S., Lampe, J. W., Bammler, T. K., Gross-Steinmeyer, K., and Eaton, D. L. Apiaceous vegetable constituents inhibit human cytochrome P-450 1A2 (hCYP1A2) activity and hCYP1A2-mediated mutagenicity of aflatoxin B1. Maljaei MB, Moosavian SP, Mirmosayyeb O, Rouhani MH, Namjoo I, Bahreini A. Lastly, celery seeds also contain magnesium and phosphorus. Here are 6 surprising benefits of celery seeds. They have a balanced macronutrient profile, offering relatively equal amounts of carbs, protein, and fat. Our Celery Seed Extract is concentrated and standardized to contain 85% 3-n-butylphthalide as total phthalides. Sultana S, Ahmed S, Jahangir T, Sharma S. Inhibitory effect of celery seeds extract on chemically induced hepatocarcinogenesis: modulation of cell proliferation, metabolism and altered hepatic foci development. Emad AM, Ali SF, Abdel-Rahman EA, et al. Eur.J Drug Metab Pharmacokinet. Indeed, celery seed is a natural alternative to synthetic repellents for protection against mosquitoes. Larger studies have linked polyphenol-rich diets to a lower occurrence of cancer, heart disease, and diabetes (1, 30). Held, J. L. Phytophotodermatitis. Without enough dietary iron, your body cannot produce enough red blood cells. Hypolipidemic and antioxidant activity of mountian celery seed essential oils. Celery seeds contain methanolic and hexane extracts, which help with circulation. View abstract. View abstract. This helps your blood vessels to expand and facilitates the smooth circulation of blood and, thus, reduces blood pressure. Ahmed B, Alam T, Varshney M, Khan SA. Celery extract replenishes lost levels of gastric mucus, keeping small holes and openings from damaging the lining of the digestive tract (x). Heck AM, DeWitt BA, Lukes AL. Bleeding may occur. Celery seeds have a spicy odor and a spicy, slightly bitter taste. A lower bone mineral density is associated with an increased risk of fractures, especially in older adults. 2004;29(2):340-6. Among other things, the minerals in celery seeds support bone health and blood sugar regulation. Supports circulation to the heart and brain*. According to Penn State University, if you are allergic to birch pollen, you are likely to also be allergic to celery seeds. Paul Pitchford, in his book "Healing with Whole Foods," recommends celery juice combined with lemon juice to treat headaches caused by high blood pressure and excessive heat. Tuetun, B., Choochote, W., Pongpaibul, Y., Junkum, A., Kanjanapothi, D., Chaithong, U., Jitpakdi, A., Riyong, D., and Pitasawat, B. Celery-based topical repellents as a potential natural alternative for personal protection against mosquitoes. Gout is triggered when uric acid builds up within the joints. 1994;130(6):809-810. Ciganda C, and Laborde A. Herbal infusions used for induced abortion. Severe phototoxic burn following celery ingestion. Rueff, F., Eberlein-Konig, B., and Przybilla, B. Advertisement references It is best to take celery seed extract in 1,000 mg increments once to three times daily, or as recommended by a doctor. Be that as it may, you should consult a physician before adding celery seed extract to your daily routine. Sides Effects of Celery Seed Extract Celery seeds extract is generally safe to consume and may promote overall health. The safety of taking celery oil and seeds if you are breastfeeding is unknown, so it's best to avoid their use if that's the case. View abstract. View abstract. 2006;44(9):1474-1484. Concerns for Pregnant Women Pregnant women should avoid large doses of celery and celery seed as it can induce bleeding and uterine contractions. Celery seeds are a great source of magnesium. Stalking hypertension. Use sunscreen or sunblock lotions. Johansson, S. G., Dannaeus, A., and Lilja, G. The relevance of anti-food antibodies for the diagnosis of food allergy. Slattery ML, Benson J, Curtin K, Ma K-N, Schaeffer D, Potter JD. Indias University College of Sciences Department of Biochemistry studied 35 commonly used Indian spices, including celery, cumin, tamarind and garlic (x). There has been no significant increase for me. It is best to take celery seed extract in 1,000 mg increments once to three times daily, or as recommended by a doctor. Healthline Media does not provide medical advice, diagnosis, or treatment. Another study observed similar antibacterial benefits of celery seed extract against certain bacteria, yeast, and mold strains. Medically reviewed by Drugs.com. Celery seed (Apium graveolens) is a time-honored remedy in traditional Indian and alternative medicine. Clin Exp Allergy 1996;26:1161-70. 3 Cancer Preventive Activity Inhibition of hepatic xanthine dehydrogenase and xanthine oxidase was suggested.Dolati 2018, Clinical trials guiding celery dosage are limited. Allergy 2002;57(3):228-235. Bull.Acad.Natl.Med 1995;179(1):161-184. Online ahead of print. Theyre low in calories and provide relatively equal amounts of carbs, protein, and fat. Parasitol.Res 2008;104(1):107-115. Egan, C. L. and Sterling, G. Phytophotodermatitis: a visit to Margaritaville. 1998;60:117-124. Experts advise against using celery seed supplements if youre pregnant, as it may cause uterine bleeding and even miscarriage (32, 33). An updated phytopharmacological review on medicinal plant of Arab region: Apium graveolens Linn. These results indicate that celery seed may help reduce gout-related inflammation. Celery seeds are a versatile spice. 2005 - 2023 WebMD LLC, an Internet Brands company. Some people who are allergic to birch pollen may also be allergic to celery seed. Clinical trials guiding celery dosage are limited. This article explores Parmesan cheese's nutritional benefits, uses, and potential. Theyre most commonly added to soups and other savory recipes, but can also be used to make tea. Consider therapy modification.Mousa 2010, Spolarilch 2007, Stanger 2012, Ulbricht 2008, Hypoglycemia-associated agents: Herbs (hypoglycemic properties) may enhance the hypoglycemic effect of hypoglycemia-associated agents. Used in cooking, celery seed spice is considered likely safe in normal quantities. Ljunggren, B. Thyroid medications: Celery seed may interact with thyroid medications. Allergy. View abstract. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Some of these include lithium, diuretics, anticoagulants and thyroid medications, according to Penn State Hershey. View abstract. Bonnin, J. P., Grezard, P., Colin, L., and Perrot, H. [A very significant case of allergy to celery]. 1986;4(3):195-199. The stem is often eaten raw or as a cooked vegetable. Nitric oxide is an important compound in the body, but it can produce oxidative stress and inflammation in large amounts. A new French multicenter study]. IMPORTANT: Celery seed and celery extract should be avoided by pregnant women. In one trial, dl-3-n-butylphthalide 400 mg orally daily (given as one 200 mg capsule twice daily) as part of a 90-day treatment regimen was used to improve outcomes in patients with acute ischemic stroke. Celery seed is contraindicated in pregnancy. Ann Trop Med Parasitol. Celery (Apium graveolens) is a plant that grows throughout the world. Im not sure what the problem is. However, various research studies may give us a starting place for beneficial dosages in humans. The drug industry uses Celery Seed Oleoresin for its anti-inflammatory View abstract. Carotenoids and colon cancer. J Midwifery Womens Health 2009;54:401-4. Discover essential oils that can aid in reducing gout symptoms. Int J Prev Med 2019;10:55. doi: 10.4103/ijpvm.IJPVM_209_17. Although herbal remedies are generally accepted as complementary and alternative therapies in combination with other medications, herbs can have side effects and interact with other herbs, supplements and medications.

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